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Annually in the conversation for most impactful defensive player in the NFL, 49ers edge rusher Nick Bosa dominated this Week 11 matchup with NFC West rival Seattle. Putting together a final stat line that included four tackles, two tackles for loss, one-and-a-half sacks, and two quarterback hits, Bosa was disruptive no matter whether the Seahawks were trying to run the ball or throw it. Despite his standout efforts, however, San Francisco would ultimately fall in this one, losing 20-17 on Nov. 17, 2024.