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Nothing beats a quick strike to spark a fourth-quarter comeback. With the Giants down 11 points to the Saints, all-purpose running back Saquon Barkley lined up out wide and turned a simple go route into a 54-yard touchdown catch and run, making multiple defenders look silly along the way. The ensuing two-point conversion cut the deficit to just three, and New York would go on to win 27-21 on Oct. 3, 2021, led by Barkley's 126 yards of total offense and two touchdowns.