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It was clear early on in the 1999 NFL Season that the St. Louis Rams offense was built different, and star receiver Isaac Bruce played a massive role in that. In Week 5 against the 49ers, Bruce put together an unforgettable performance, scoring four times and accruing 134 receiving yards on just five catches, taking over the game early with three first quarter touchdowns before adding a fourth to put the game away in the fourth quarter. St. Louis would ultimately win this matchup against San Francisco, 42-20, on Oct. 10, 1999.